Endocrine Abstracts

Opiate use is a well-recognised cause of hypogonadotrophic hypogonadism. Adrenocorticotrophic hormone and growth hormone deficiencies are much rarer.A 56-year-old female presented with weight loss, lethargy, and nausea of ~3 years duration. She had received treatment with morphine sulphate 100 mg twice daily for ~15 years for back pain due to disc prolapse and osteoarthritis. A 0900 h cortisol of 110 nmol/l requested by her general practitioner had resul...

Immobilisation is a recognised but rare cause of hypercalcaemia. Most reported cases are patients with spinal cord injury or trauma.Case 1: A 26-year-old female experienced a 5½ months admission to the intensive care unit (ITU) with complications following small bowel resection for Crohn’s disease. At 16 weeks she developed hypercalcaemia. Investigations confirmed calcium 3.24 mmol/l, parathyroid hormone (PTH) <0.6 pmol/l (1.6–6.9), 24...